Vomeronasal type-1 receptor 4 (VN1R4)
Homo sapiens — UniProt Q7Z5H5
Data last refreshed: (UniProt release unknown)
Key facts
Vomeronasal type-1 receptor 4 (VN1R4) is a protein from Homo sapiens identified by UniProt accession Q7Z5H5, 301 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q7Z5H5; gene symbol VN1R4.
- Organism: Homo sapiens.
- Length: 301 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, infection and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vomeronasal type-1 receptor 4 |
|---|---|
| UniProt accession | Q7Z5H5 |
| Gene | VN1R4 |
| Organism | Homo sapiens |
| Length | 301 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- infection · score 0.00
- infect · score 0.00
- pneumocystosis · score 0.00
- Pneumocystis infectious disease · score 0.00
- Langer mesomelic dysplasia · score 0.00
- cancer · score 0.00
- hemochromatosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5H5-F1 | alphafold | PREDICTED | 77.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5H5.
Amino-acid sequence (301 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VN1R4?
The strongest Open Targets associations for VN1R4 are neurodegenerative disease, infection, infect, pneumocystosis and Pneumocystis infectious disease.
How long is the VN1R4 protein?
The Homo sapiens VN1R4 protein (UniProt Q7Z5H5) is 301 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5H5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5H5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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