Ankyrin and armadillo repeat-containing protein (ANKAR)
Homo sapiens — UniProt Q7Z5J8
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin and armadillo repeat-containing protein (ANKAR) is a protein from Homo sapiens identified by UniProt accession Q7Z5J8, 1434 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q7Z5J8; gene symbol ANKAR.
- Organism: Homo sapiens.
- Length: 1434 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, ferritin measurement and liver iron measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin and armadillo repeat-containing protein |
|---|---|
| UniProt accession | Q7Z5J8 |
| Gene | ANKAR |
| Organism | Homo sapiens |
| Length | 1434 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.20
- ferritin measurement · score 0.13
- liver iron measurement · score 0.05
- hemochromatosis type 4 · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5J8-F1 | alphafold | PREDICTED | 84.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5J8.
Amino-acid sequence (1434 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKAR?
The strongest Open Targets associations for ANKAR are Red cell distribution width, ferritin measurement, liver iron measurement and hemochromatosis type 4.
How long is the ANKAR protein?
The Homo sapiens ANKAR protein (UniProt Q7Z5J8) is 1434 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5J8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5J8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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