Vitelline membrane outer layer protein 1 homolog (VMO1)
Homo sapiens — UniProt Q7Z5L0
Data last refreshed: (UniProt release unknown)
Key facts
Vitelline membrane outer layer protein 1 homolog (VMO1) is a protein from Homo sapiens identified by UniProt accession Q7Z5L0, 202 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q7Z5L0; gene symbol VMO1.
- Organism: Homo sapiens.
- Length: 202 amino acids.
- Top disease associations (Open Targets): blood protein measurement, low density lipoprotein cholesterol measurement and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vitelline membrane outer layer protein 1 homolog |
|---|---|
| UniProt accession | Q7Z5L0 |
| Gene | VMO1 |
| Organism | Homo sapiens |
| Length | 202 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.26
- low density lipoprotein cholesterol measurement · score 0.19
- serum gamma-glutamyl transferase measurement · score 0.19
- triglyceride measurement · score 0.07
- C-X-C motif chemokine 16 measurement · score 0.06
- sphingolipid measurement · score 0.05
- Acute hepatic failure · score 0.03
- coronary artery calcification · score 0.02
- lung adenocarcinoma · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5L0-F1 | alphafold | PREDICTED | 82.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5L0.
Amino-acid sequence (202 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VMO1?
The strongest Open Targets associations for VMO1 are blood protein measurement, low density lipoprotein cholesterol measurement, serum gamma-glutamyl transferase measurement, triglyceride measurement and C-X-C motif chemokine 16 measurement.
How long is the VMO1 protein?
The Homo sapiens VMO1 protein (UniProt Q7Z5L0) is 202 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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