Complement C1q-like protein 2 (C1QL2)
Homo sapiens — UniProt Q7Z5L3
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q-like protein 2 (C1QL2) is a protein from Homo sapiens identified by UniProt accession Q7Z5L3, 287 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q7Z5L3; gene symbol C1QL2.
- Organism: Homo sapiens.
- Length: 287 amino acids.
- Top disease associations (Open Targets): response to cetuximab, skin disease and colon carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q-like protein 2 |
|---|---|
| UniProt accession | Q7Z5L3 |
| Gene | C1QL2 |
| Organism | Homo sapiens |
| Length | 287 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- response to cetuximab · score 0.26
- skin disease · score 0.26
- colon carcinoma · score 0.26
- metabolite measurement · score 0.16
- cortical thickness · score 0.12
- body height · score 0.10
- Female infertility due to fertilization defect · score 0.05
- kidney disease · score 0.04
- female infertility due to oocyte meiotic arrest · score 0.04
- bone density · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5L3-F1 | alphafold | PREDICTED | 74.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5L3.
Amino-acid sequence (287 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QL2?
The strongest Open Targets associations for C1QL2 are response to cetuximab, skin disease, colon carcinoma, metabolite measurement and cortical thickness.
How long is the C1QL2 protein?
The Homo sapiens C1QL2 protein (UniProt Q7Z5L3) is 287 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5L3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5L3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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