Spermatogenesis-associated protein 19, mitochondrial (SPATA19)
Homo sapiens — UniProt Q7Z5L4
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-associated protein 19, mitochondrial (SPATA19) is a protein from Homo sapiens identified by UniProt accession Q7Z5L4, 167 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q7Z5L4; gene symbol SPATA19.
- Organism: Homo sapiens.
- Length: 167 amino acids.
- Top disease associations (Open Targets): body mass index, alcohol consumption measurement and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-associated protein 19, mitochondrial |
|---|---|
| UniProt accession | Q7Z5L4 |
| Gene | SPATA19 |
| Organism | Homo sapiens |
| Length | 167 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- body mass index · score 0.46
- alcohol consumption measurement · score 0.34
- body fat percentage · score 0.33
- diet measurement · score 0.30
- hip circumference · score 0.28
- fat body mass · score 0.25
- protein measurement · score 0.24
- body height · score 0.22
- cognitive function measurement · score 0.21
- self reported educational attainment · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5L4-F1 | alphafold | PREDICTED | 69.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5L4.
Amino-acid sequence (167 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA19?
The strongest Open Targets associations for SPATA19 are body mass index, alcohol consumption measurement, body fat percentage, diet measurement and hip circumference.
How long is the SPATA19 protein?
The Homo sapiens SPATA19 protein (UniProt Q7Z5L4) is 167 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5L4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5L4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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