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Podocan (PODN)

Homo sapiens — UniProt Q7Z5L7

Gene: PODNHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Podocan (PODN) is a protein from Homo sapiens identified by UniProt accession Q7Z5L7, 613 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

  • UniProt accession: Q7Z5L7; gene symbol PODN.
  • Organism: Homo sapiens.
  • Length: 613 amino acids.
  • Top disease associations (Open Targets): body height, tuberculin skin test reactivity measurement and Familial prostate cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePodocan
UniProt accessionQ7Z5L7
GenePODN
OrganismHomo sapiens
Length613 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (69)

Diseases linked to this target (Open Targets).

  • body height · score 0.31
  • tuberculin skin test reactivity measurement · score 0.16
  • Familial prostate cancer · score 0.11
  • prostate cancer · score 0.11
  • prostate carcinoma · score 0.11
  • forced expiratory volume · score 0.09
  • Familial ocular anterior segment mesenchymal dysgenesis · score 0.06
  • Rieger anomaly · score 0.04
  • iridocorneal endothelial syndrome · score 0.04
  • posterior amorphous corneal dystrophy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z5L7-F1alphafoldPREDICTED86.57—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5L7.

Amino-acid sequence (613 residues)

MAQSRVLLLL LLLPPQLHLG PVLAVRAPGF GRSGGHSLSP EENEFAEEEP VLVLSPEEPG PGPAAVSCPR DCACSQEGVV DCGGIDLREF PGDLPEHTNH LSLQNNQLEK IYPEELSRLH RLETLNLQNN RLTSRGLPEK AFEHLTNLNY LYLANNKLTL APRFLPNALI SVDFAANYLT KIYGLTFGQK PNLRSVYLHN NKLADAGLPD NMFNGSSNVE VLILSSNFLR HVPKHLPPAL YKLHLKNNKL EKIPPGAFSE LSSLRELYLQ NNYLTDEGLD NETFWKLSSL EYLDLSSNNL SRVPAGLPRS LVLLHLEKNA IRSVDANVLT PIRSLEYLLL HSNQLREQGI HPLAFQGLKR LHTVHLYNNA LERVPSGLPR RVRTLMILHN QITGIGREDF ATTYFLEELN LSYNRITSPQ VHRDAFRKLR LLRSLDLSGN RLHTLPPGLP RNVHVLKVKR NELAALARGA LVGMAQLREL YLTSNRLRSR ALGPRAWVDL AHLQLLDIAG NQLTEIPEGL PESLEYLYLQ NNKISAVPAN AFDSTPNLKG IFLRFNKLAV GSVVDSAFRR LKHLQVLDIE GNLEFGDISK DRGRLGKEKE EEEEEEEEEE ETR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PODN?

The strongest Open Targets associations for PODN are body height, tuberculin skin test reactivity measurement, Familial prostate cancer, prostate cancer and prostate carcinoma.

How long is the PODN protein?

The Homo sapiens PODN protein (UniProt Q7Z5L7) is 613 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z5L7
GenePODN
OrganismHomo sapiens
Length613
Binders0
Diseases69
View on UniProt