Interferon regulatory factor 2-binding protein 2 (IRF2BP2)
Homo sapiens — UniProt Q7Z5L9
Data last refreshed: (UniProt release unknown)
Key facts
Interferon regulatory factor 2-binding protein 2 (IRF2BP2) is a protein from Homo sapiens identified by UniProt accession Q7Z5L9, 587 residues long. MolForge cross-references it against 0 known binders and 163 disease associations.
- UniProt accession: Q7Z5L9; gene symbol IRF2BP2.
- Organism: Homo sapiens.
- Length: 587 amino acids.
- Top disease associations (Open Targets): immunodeficiency, common variable, 14, common variable immunodeficiency and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interferon regulatory factor 2-binding protein 2 |
|---|---|
| UniProt accession | Q7Z5L9 |
| Gene | IRF2BP2 |
| Organism | Homo sapiens |
| Length | 587 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (163)
Diseases linked to this target (Open Targets).
- immunodeficiency, common variable, 14 · score 0.62
- common variable immunodeficiency · score 0.56
- low density lipoprotein cholesterol measurement · score 0.41
- total cholesterol measurement · score 0.40
- mean corpuscular volume · score 0.38
- Red cell distribution width · score 0.38
- alkaline phosphatase measurement · score 0.37
- apolipoprotein B measurement · score 0.37
- monocyte percentage of leukocytes · score 0.36
- neutrophil count · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5L9-F1 | alphafold | PREDICTED | 55.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5L9.
Amino-acid sequence (587 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IRF2BP2?
The strongest Open Targets associations for IRF2BP2 are immunodeficiency, common variable, 14, common variable immunodeficiency, low density lipoprotein cholesterol measurement, total cholesterol measurement and mean corpuscular volume.
How long is the IRF2BP2 protein?
The Homo sapiens IRF2BP2 protein (UniProt Q7Z5L9) is 587 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5L9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5L9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.