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Cytoplasmic polyadenylation element-binding protein 2 (CPEB2)

Homo sapiens — UniProt Q7Z5Q1

Gene: CPEB2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cytoplasmic polyadenylation element-binding protein 2 (CPEB2) is a protein from Homo sapiens identified by UniProt accession Q7Z5Q1, 589 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

  • UniProt accession: Q7Z5Q1; gene symbol CPEB2.
  • Organism: Homo sapiens.
  • Length: 589 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, triglyceride measurement and mean platelet volume.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCytoplasmic polyadenylation element-binding protein 2
UniProt accessionQ7Z5Q1
GeneCPEB2
OrganismHomo sapiens
Length589 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.34
  • triglyceride measurement · score 0.33
  • mean platelet volume · score 0.32
  • self reported educational attainment · score 0.32
  • neurodegenerative disease · score 0.31
  • systolic blood pressure · score 0.30
  • IGF-1 measurement · score 0.29
  • serum albumin measurement · score 0.27
  • high density lipoprotein cholesterol measurement · score 0.26
  • cardiovascular disease · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z5Q1-F1alphafoldPREDICTED61.37—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5Q1.

Amino-acid sequence (589 residues)

MPPPSPDSEN GFYPGLPSSM NPAFFPSFSP VSPHGCTGLS VPTSGGGGGG FGGPFSATAV PPPPPPAMNI PQQQPPPPAA PQQPQSRRSP VSPQLQQQHQ AAAAAFLQQR NSYNHHQPLL KQSPWSNHQS SGWGTGSMSW GAMHGRDHRR TGNMGIPGTM NQISPLKKPF SGNVIAPPKF TRSTPSLTPK SWIEDNVFRT DNNSNTLLPL QVRSSLQLPA WGSDSLQDSW CTAAGTSRID QDRSRMYDSL NMHSLENSLI DIMRAEHDPL KGRLSYPHPG TDNLLMLNGR SSLFPIDDGL LDDGHSDQVG VLNSPTCYSA HQNGERIERF SRKVFVGGLP PDIDEDEITA SFRRFGPLVV DWPHKAESKS YFPPKGYAFL LFQEESSVQA LIDACIEEDG KLYLCVSSPT IKDKPVQIRP WNLSDSDFVM DGSQPLDPRK TIFVGGVPRP LRAVELAMIM DRLYGGVCYA GIDTDPELKY PKGAGRVAFS NQQSYIAAIS ARFVQLQHGD IDKRVEVKPY VLDDQMCDEC QGARCGGKFA PFFCANVTCL QYYCEFCWAN IHSRAGREFH KPLVKEGADR PRQIHFRWN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CPEB2?

The strongest Open Targets associations for CPEB2 are heel bone mineral density, triglyceride measurement, mean platelet volume, self reported educational attainment and neurodegenerative disease.

How long is the CPEB2 protein?

The Homo sapiens CPEB2 protein (UniProt Q7Z5Q1) is 589 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z5Q1
GeneCPEB2
OrganismHomo sapiens
Length589
Binders0
Diseases62
View on UniProt