Transmembrane protein 144 (TMEM144)
Homo sapiens — UniProt Q7Z5S9
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 144 (TMEM144) is a protein from Homo sapiens identified by UniProt accession Q7Z5S9, 345 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q7Z5S9; gene symbol TMEM144.
- Organism: Homo sapiens.
- Length: 345 amino acids.
- Top disease associations (Open Targets): reticulocyte count, reticulocyte measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 144 |
|---|---|
| UniProt accession | Q7Z5S9 |
| Gene | TMEM144 |
| Organism | Homo sapiens |
| Length | 345 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.15
- reticulocyte measurement · score 0.14
- self reported educational attainment · score 0.09
- blood protein measurement · score 0.02
- pulse pressure measurement · score 0.02
- atypical teratoid rhabdoid tumor · score 0.02
- medulloblastoma · score 0.01
- cancer · score 0.01
- neoplasm · score 0.01
- oligodendroglioma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5S9-F1 | alphafold | PREDICTED | 88.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5S9.
Amino-acid sequence (345 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM144?
The strongest Open Targets associations for TMEM144 are reticulocyte count, reticulocyte measurement, self reported educational attainment, blood protein measurement and pulse pressure measurement.
How long is the TMEM144 protein?
The Homo sapiens TMEM144 protein (UniProt Q7Z5S9) is 345 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5S9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5S9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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