Stabilizer of axonemal microtubules 4 (SAXO4)
Homo sapiens — UniProt Q7Z5V6
Data last refreshed: (UniProt release unknown)
Key facts
Stabilizer of axonemal microtubules 4 (SAXO4) is a protein from Homo sapiens identified by UniProt accession Q7Z5V6, 425 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q7Z5V6; gene symbol SAXO4.
- Organism: Homo sapiens.
- Length: 425 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, Griscelli syndrome type 3 and Griscelli disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stabilizer of axonemal microtubules 4 |
|---|---|
| UniProt accession | Q7Z5V6 |
| Gene | SAXO4 |
| Organism | Homo sapiens |
| Length | 425 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.11
- Griscelli syndrome type 3 · score 0.06
- Griscelli disease · score 0.05
- Griscelli disease type 3 · score 0.05
- piebald trait-neurologic defects syndrome · score 0.05
- uncombable hair syndrome · score 0.05
- refractive error measurement · score 0.05
- oculocutaneous albinism type 3 · score 0.05
- Piebald trait - neurologic defects · score 0.04
- Griscelli disease type 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5V6-F1 | alphafold | PREDICTED | 55.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5V6.
Amino-acid sequence (425 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAXO4?
The strongest Open Targets associations for SAXO4 are diastolic blood pressure, Griscelli syndrome type 3, Griscelli disease, Griscelli disease type 3 and piebald trait-neurologic defects syndrome.
How long is the SAXO4 protein?
The Homo sapiens SAXO4 protein (UniProt Q7Z5V6) is 425 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5V6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5V6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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