BTB/POZ domain-containing protein KCTD20 (KCTD20)
Homo sapiens — UniProt Q7Z5Y7
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein KCTD20 (KCTD20) is a protein from Homo sapiens identified by UniProt accession Q7Z5Y7, 419 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q7Z5Y7; gene symbol KCTD20.
- Organism: Homo sapiens.
- Length: 419 amino acids.
- Top disease associations (Open Targets): mean platelet volume, platelet count and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein KCTD20 |
|---|---|
| UniProt accession | Q7Z5Y7 |
| Gene | KCTD20 |
| Organism | Homo sapiens |
| Length | 419 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.35
- platelet count · score 0.35
- platelet component distribution width · score 0.22
- platelet-to-lymphocyte ratio · score 0.16
- airway imaging measurement · score 0.10
- drug use measurement · score 0.04
- hematocrit · score 0.04
- hemoglobin measurement · score 0.04
- mean corpuscular volume · score 0.02
- non-small cell lung carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5Y7-F1 | alphafold | PREDICTED | 70.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5Y7.
Amino-acid sequence (419 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCTD20?
The strongest Open Targets associations for KCTD20 are mean platelet volume, platelet count, platelet component distribution width, platelet-to-lymphocyte ratio and airway imaging measurement.
How long is the KCTD20 protein?
The Homo sapiens KCTD20 protein (UniProt Q7Z5Y7) is 419 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5Y7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5Y7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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