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Calmodulin-lysine N-methyltransferase (CAMKMT)

Homo sapiens — UniProt Q7Z624

Gene: CAMKMTHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Calmodulin-lysine N-methyltransferase (CAMKMT) is a protein from Homo sapiens identified by UniProt accession Q7Z624, 323 residues long. MolForge cross-references it against 0 known binders and 172 disease associations.

  • UniProt accession: Q7Z624; gene symbol CAMKMT.
  • Organism: Homo sapiens.
  • Length: 323 amino acids.
  • Top disease associations (Open Targets): body height, self reported educational attainment and age at first sexual intercourse measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCalmodulin-lysine N-methyltransferase
UniProt accessionQ7Z624
GeneCAMKMT
OrganismHomo sapiens
Length323 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (172)

Diseases linked to this target (Open Targets).

  • body height · score 0.43
  • self reported educational attainment · score 0.41
  • age at first sexual intercourse measurement · score 0.40
  • chronotype measurement · score 0.39
  • hypotonia-cystinuria syndrome · score 0.37
  • Hypotonia - cystinuria syndrome · score 0.37
  • Atypical hypotonia - cystinuria syndrome · score 0.37
  • body mass index · score 0.37
  • bone density · score 0.37
  • urate measurement · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z624-F1alphafoldPREDICTED84.82—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z624.

Amino-acid sequence (323 residues)

MESRVADAGT GETARAAGGS PAVGCTTRGP VVSAPLGAAR WKLLRQVLKQ KHLDDCLRHV SVRRFESFNL FSVTEGKERE TEEEVGAWVQ YTSIFCPEYS ISLRHNSGSL NVEDVLTSFD NTGNVCIWPS EEVLAYYCLK HNNIFRALAV CELGGGMTCL AGLMVAISAD VKEVLLTDGN EKAIRNVQDI ITRNQKAGVF KTQKISSCVL RWDNETDVSQ LEGHFDIVMC ADCLFLDQYR ASLVDAIKRL LQPRGKAMVF APRRGNTLNQ FCNLAEKAGF CIQRHENYDE HISNFHSKLK KENPDIYEEN LHYPLLLILT KHG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CAMKMT?

The strongest Open Targets associations for CAMKMT are body height, self reported educational attainment, age at first sexual intercourse measurement, chronotype measurement and hypotonia-cystinuria syndrome.

How long is the CAMKMT protein?

The Homo sapiens CAMKMT protein (UniProt Q7Z624) is 323 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z624
GeneCAMKMT
OrganismHomo sapiens
Length323
Binders0
Diseases172
View on UniProt