Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B)
Homo sapiens — UniProt Q7Z6G8
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B) is a protein from Homo sapiens identified by UniProt accession Q7Z6G8, 1248 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q7Z6G8; gene symbol ANKS1B.
- Organism: Homo sapiens.
- Length: 1248 amino acids.
- Top disease associations (Open Targets): handedness, total blood protein measurement and insomnia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and sterile alpha motif domain-containing protein 1B |
|---|---|
| UniProt accession | Q7Z6G8 |
| Gene | ANKS1B |
| Organism | Homo sapiens |
| Length | 1248 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- handedness · score 0.38
- total blood protein measurement · score 0.29
- insomnia · score 0.29
- body mass index · score 0.28
- gut microbiome measurement · score 0.28
- body fat percentage · score 0.24
- body weight · score 0.24
- bipolar disorder · score 0.23
- schizophrenia · score 0.22
- lean body mass · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6G8-F1 | alphafold | PREDICTED | 56.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6G8.
Amino-acid sequence (1248 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKS1B?
The strongest Open Targets associations for ANKS1B are handedness, total blood protein measurement, insomnia, body mass index and gut microbiome measurement.
How long is the ANKS1B protein?
The Homo sapiens ANKS1B protein (UniProt Q7Z6G8) is 1248 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6G8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6G8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.