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UPF0461 protein C5orf24 (C5orf24)

Homo sapiens — UniProt Q7Z6I8

Gene: C5orf24Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

UPF0461 protein C5orf24 (C5orf24) is a protein from Homo sapiens identified by UniProt accession Q7Z6I8, 188 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

  • UniProt accession: Q7Z6I8; gene symbol C5orf24.
  • Organism: Homo sapiens.
  • Length: 188 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, Parkinson disease and age at voice drop.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUPF0461 protein C5orf24
UniProt accessionQ7Z6I8
GeneC5orf24
OrganismHomo sapiens
Length188 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (9)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.10
  • Parkinson disease · score 0.04
  • age at voice drop · score 0.03
  • Thymoma · score 0.03
  • vital capacity · score 0.02
  • chronic kidney disease · score 0.01
  • post-traumatic stress disorder · score 0.01
  • pulmonary tuberculosis · score 0.00
  • pancreatic ductal adenocarcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z6I8-F1alphafoldPREDICTED55.09—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6I8.

Amino-acid sequence (188 residues)

MMHPVASSNP AFCGPGKPSC LNEDAMRAAD QFDIYSSQQS KYSHTVNHKP MVCQRQDPLN ETHLQTTSGR SIEIKDELKK KKNLNRSGKR GRPSGTTKSA GYRTSTGRPL GTTKAAGFKT SPGRPLGTTK AAGYKVSPGR PPGSIKALSR LADLGYGCGT AAFPYPMMHG RAVHGVEETS SEVKPPNE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C5orf24?

The strongest Open Targets associations for C5orf24 are neurodegenerative disease, Parkinson disease, age at voice drop, Thymoma and vital capacity.

How long is the C5orf24 protein?

The Homo sapiens C5orf24 protein (UniProt Q7Z6I8) is 188 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z6I8
GeneC5orf24
OrganismHomo sapiens
Length188
Binders0
Diseases9
View on UniProt