FERM domain-containing protein 5 (FRMD5)
Homo sapiens — UniProt Q7Z6J6
Data last refreshed: (UniProt release unknown)
Key facts
FERM domain-containing protein 5 (FRMD5) is a protein from Homo sapiens identified by UniProt accession Q7Z6J6, 570 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.
- UniProt accession: Q7Z6J6; gene symbol FRMD5.
- Organism: Homo sapiens.
- Length: 570 amino acids.
- Top disease associations (Open Targets): neurodevelopmental disorder with eye movement abnormalities and ataxia, triglyceride measurement and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FERM domain-containing protein 5 |
|---|---|
| UniProt accession | Q7Z6J6 |
| Gene | FRMD5 |
| Organism | Homo sapiens |
| Length | 570 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (94)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with eye movement abnormalities and ataxia · score 0.67
- triglyceride measurement · score 0.37
- neurodegenerative disease · score 0.33
- sphingomyelin measurement · score 0.31
- lipoprotein-associated phospholipase A(2) measurement · score 0.31
- high density lipoprotein cholesterol measurement · score 0.30
- hemoglobin measurement · score 0.29
- alkaline phosphatase measurement · score 0.25
- serum albumin measurement · score 0.24
- sleep duration · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6J6-F1 | alphafold | PREDICTED | 74.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6J6.
Amino-acid sequence (570 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FRMD5?
The strongest Open Targets associations for FRMD5 are neurodevelopmental disorder with eye movement abnormalities and ataxia, triglyceride measurement, neurodegenerative disease, sphingomyelin measurement and lipoprotein-associated phospholipase A(2) measurement.
How long is the FRMD5 protein?
The Homo sapiens FRMD5 protein (UniProt Q7Z6J6) is 570 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6J6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6J6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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