Protein prenyltransferase alpha subunit repeat-containing protein 1 (PTAR1)
Homo sapiens — UniProt Q7Z6K3
Data last refreshed: (UniProt release unknown)
Key facts
Protein prenyltransferase alpha subunit repeat-containing protein 1 (PTAR1) is a protein from Homo sapiens identified by UniProt accession Q7Z6K3, 402 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q7Z6K3; gene symbol PTAR1.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, intraocular pressure measurement and CD5 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein prenyltransferase alpha subunit repeat-containing protein 1 |
|---|---|
| UniProt accession | Q7Z6K3 |
| Gene | PTAR1 |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- intraocular pressure measurement · score 0.03
- CD5 measurement · score 0.03
- corneal resistance factor · score 0.02
- cognitive function measurement · score 0.02
- protein measurement · score 0.02
- bone density · score 0.02
- acute quadriplegic myopathy · score 0.00
- cancer · score 0.00
- adult T-cell leukemia/lymphoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6K3-F1 | alphafold | PREDICTED | 83.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6K3.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PTAR1?
The strongest Open Targets associations for PTAR1 are neurodegenerative disease, intraocular pressure measurement, CD5 measurement, corneal resistance factor and cognitive function measurement.
How long is the PTAR1 protein?
The Homo sapiens PTAR1 protein (UniProt Q7Z6K3) is 402 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6K3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6K3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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