Tectonin beta-propeller repeat-containing protein 1 (TECPR1)
Homo sapiens — UniProt Q7Z6L1
Data last refreshed: (UniProt release unknown)
Key facts
Tectonin beta-propeller repeat-containing protein 1 (TECPR1) is a protein from Homo sapiens identified by UniProt accession Q7Z6L1, 1165 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q7Z6L1; gene symbol TECPR1.
- Organism: Homo sapiens.
- Length: 1165 amino acids.
- Top disease associations (Open Targets): Tracheoesophageal fistula, erythrocyte count and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tectonin beta-propeller repeat-containing protein 1 |
|---|---|
| UniProt accession | Q7Z6L1 |
| Gene | TECPR1 |
| Organism | Homo sapiens |
| Length | 1165 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- Tracheoesophageal fistula · score 0.26
- erythrocyte count · score 0.23
- urate measurement · score 0.20
- heel bone mineral density · score 0.19
- monocyte percentage of leukocytes · score 0.17
- monocyte count · score 0.13
- lymphocyte count · score 0.11
- bilirubin measurement · score 0.11
- sex hormone-binding globulin measurement · score 0.09
- neutrophil percentage of leukocytes · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6L1-F1 | alphafold | PREDICTED | 78.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6L1.
Amino-acid sequence (1165 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TECPR1?
The strongest Open Targets associations for TECPR1 are Tracheoesophageal fistula, erythrocyte count, urate measurement, heel bone mineral density and monocyte percentage of leukocytes.
How long is the TECPR1 protein?
The Homo sapiens TECPR1 protein (UniProt Q7Z6L1) is 1165 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6L1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6L1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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