F-box only protein 33 (FBXO33)
Homo sapiens — UniProt Q7Z6M2
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 33 (FBXO33) is a protein from Homo sapiens identified by UniProt accession Q7Z6M2, 555 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q7Z6M2; gene symbol FBXO33.
- Organism: Homo sapiens.
- Length: 555 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, body height and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 33 |
|---|---|
| UniProt accession | Q7Z6M2 |
| Gene | FBXO33 |
| Organism | Homo sapiens |
| Length | 555 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.37
- body height · score 0.30
- body mass index · score 0.26
- systolic blood pressure · score 0.22
- leukocyte count · score 0.13
- upper respiratory tract disorder · score 0.13
- monocyte count · score 0.09
- body fat percentage · score 0.08
- platelet component distribution width · score 0.08
- platelet count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6M2-F1 | alphafold | PREDICTED | 81.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6M2.
Amino-acid sequence (555 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO33?
The strongest Open Targets associations for FBXO33 are appendicular lean mass, body height, body mass index, systolic blood pressure and leukocyte count.
How long is the FBXO33 protein?
The Homo sapiens FBXO33 protein (UniProt Q7Z6M2) is 555 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6M2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6M2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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