About Ras-related protein Rab-44
Ras-related protein Rab-44 (RAB44) is a protein
from Homo sapiens identified by UniProt accession
Q7Z6P3, 1021 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (53)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.17
- uterine fibroid · score 0.15
- systemic lupus erythematosus · score 0.13
- Uterine leiomyoma · score 0.13
- serum alanine aminotransferase measurement · score 0.12
- serum gamma-glutamyl transferase measurement · score 0.10
- QRS duration · score 0.09
- QT interval · score 0.09
- QRS complex · score 0.08
- QRS amplitude · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q7Z6P3.
Amino-acid sequence (1021 residues)
METGQRTSRK VRKLGSNRRR QTREPADGEG AAVAPEPESW SSQAAAELQA FFQDCGAKER GFVTREDLAV AKFSFLGSKE ESEMIFDWVD VERKGHLSLE EFSSGLKNIF GSSQSPHRLR RRKPLPSKRV SATTSFPALE EADAEEKEAF LAFMEQLGTG HLLPKQMEIW QLWGQLRQEE PQLAGNLAGF LAKMTSRLQE AQADKEALEL TLRKRDSDHH REVQQLYEEM EQQIRQEKQQ LQAESDSRGL ALTSQMQDVL EAKEREVQRL AEGQRELEAQ LSHLRSTHQE AASENQQLQE AKRDLAGRLE EVRGQLQVTR GRLDAARGRV SWQVEEKLSF PGAGEKTPDP QAASPEEAPL PGLFGDNDDW DQLLSNFGSP PHGALQLCWS PPPTPRATSG PQTPRVVRQI SISEPQAFLF GQEPSSDPDG APRTPPGVTF SAKDNKGVDP HEQDIRAEQP VEPHDPDPNQ EPGSTPEGRL LWGLSGSLVA PAFKVLIPLE DGPPPPANSP PPQAPAGSSK QIQASDPDDK GPGSWAPPSG AQPGAGAGPQ EPTQTPPTMT ERETQPGPSP TTALTGVGPA KPPRQRDALQ QDLHATGSEP RLGTQRARAL TLGPAEPFQG LEFVGPVPTE RLEQGQAGPA VQEGLPEGLR EAHGQVLGLG ELSAFPHQEL EEEPRSEEGK QEGRGGQDLS SEQSEQSVEA HGLETAHSEL PQQDSLLVSL PSATPQAQVE AEGPTPGKSA PPRGSPPRGA QPGAGAGPQE PTQTPPTMAE QEAQPRPSLT TAHAEEQGPP HSREPRAESR LEDPGMDSRE AGLTPSPGDP MAGGGPQANP DYLFHVIFLG DSNVGKTSFL HLLHQNSFAT GLTATVGVDF RVKTLLVDNK CFVLQLWDTA GQERYHSMTR QLLRKADGVV LMYDITSQES FAHVRYWLDC LQDAGSDGVV ILLLGNKMDC EEERQVSVEA GQQLAQELGV YFGECSAALG HNILEPVVNL ARSLRMQEEG LKDSLVKVAP KRPPKRFGCC S
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