tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2 (ADAT2)
Homo sapiens — UniProt Q7Z6V5
Data last refreshed: (UniProt release unknown)
Key facts
tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2 (ADAT2) is a protein from Homo sapiens identified by UniProt accession Q7Z6V5, 191 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q7Z6V5; gene symbol ADAT2.
- Organism: Homo sapiens.
- Length: 191 amino acids.
- Top disease associations (Open Targets): chronotype measurement, self reported educational attainment and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2 |
|---|---|
| UniProt accession | Q7Z6V5 |
| Gene | ADAT2 |
| Organism | Homo sapiens |
| Length | 191 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.26
- self reported educational attainment · score 0.24
- PHF-tau measurement · score 0.19
- neurodegenerative disease · score 0.18
- peroxisome biogenesis disorder 1A (Zellweger) · score 0.12
- Inguinal hernia · score 0.09
- pulse pressure measurement · score 0.08
- aortic measurement · score 0.08
- diastolic blood pressure · score 0.05
- Hernia of the abdominal wall · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6V5-F1 | alphafold | PREDICTED | 89.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6V5.
Amino-acid sequence (191 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADAT2?
The strongest Open Targets associations for ADAT2 are chronotype measurement, self reported educational attainment, PHF-tau measurement, neurodegenerative disease and peroxisome biogenesis disorder 1A (Zellweger).
How long is the ADAT2 protein?
The Homo sapiens ADAT2 protein (UniProt Q7Z6V5) is 191 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6V5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6V5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.