Transmembrane and coiled-coil domain-containing protein 2 (TMCO2)
Homo sapiens — UniProt Q7Z6W1
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane and coiled-coil domain-containing protein 2 (TMCO2) is a protein from Homo sapiens identified by UniProt accession Q7Z6W1, 182 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q7Z6W1; gene symbol TMCO2.
- Organism: Homo sapiens.
- Length: 182 amino acids.
- Top disease associations (Open Targets): body mass index and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane and coiled-coil domain-containing protein 2 |
|---|---|
| UniProt accession | Q7Z6W1 |
| Gene | TMCO2 |
| Organism | Homo sapiens |
| Length | 182 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- body mass index · score 0.08
- lymphocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6W1-F1 | alphafold | PREDICTED | 61.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6W1.
Amino-acid sequence (182 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMCO2?
The strongest Open Targets associations for TMCO2 are body mass index and lymphocyte count.
How long is the TMCO2 protein?
The Homo sapiens TMCO2 protein (UniProt Q7Z6W1) is 182 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6W1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6W1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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