DnaJ homolog subfamily B member 7 (DNAJB7)
Homo sapiens — UniProt Q7Z6W7
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily B member 7 (DNAJB7) is a protein from Homo sapiens identified by UniProt accession Q7Z6W7, 309 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q7Z6W7; gene symbol DNAJB7.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, total cholesterol measurement and bipolar disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily B member 7 |
|---|---|
| UniProt accession | Q7Z6W7 |
| Gene | DNAJB7 |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.21
- total cholesterol measurement · score 0.17
- bipolar disorder · score 0.16
- low density lipoprotein cholesterol measurement · score 0.16
- C-reactive protein measurement · score 0.15
- apolipoprotein B measurement · score 0.13
- neoplasm · score 0.08
- MODY · score 0.06
- refractive error · score 0.06
- colorectal adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z6W7-F1 | alphafold | PREDICTED | 58.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z6W7.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJB7?
The strongest Open Targets associations for DNAJB7 are vitamin D measurement, total cholesterol measurement, bipolar disorder, low density lipoprotein cholesterol measurement and C-reactive protein measurement.
How long is the DNAJB7 protein?
The Homo sapiens DNAJB7 protein (UniProt Q7Z6W7) is 309 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z6W7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z6W7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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