Ankyrin repeat domain-containing protein 37 (ANKRD37)
Homo sapiens — UniProt Q7Z713
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 37 (ANKRD37) is a protein from Homo sapiens identified by UniProt accession Q7Z713, 158 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q7Z713; gene symbol ANKRD37.
- Organism: Homo sapiens.
- Length: 158 amino acids.
- Top disease associations (Open Targets): systemic scleroderma, esophageal squamous cell carcinoma and preeclampsia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 37 |
|---|---|
| UniProt accession | Q7Z713 |
| Gene | ANKRD37 |
| Organism | Homo sapiens |
| Length | 158 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- systemic scleroderma · score 0.16
- esophageal squamous cell carcinoma · score 0.03
- preeclampsia · score 0.02
- childhood trauma measurement · score 0.02
- smoking behaviour measurement · score 0.02
- psoriasis · score 0.01
- diffuse large B-cell lymphoma · score 0.01
- oral squamous cell carcinoma · score 0.01
- tuberculosis · score 0.01
- Iron deficiency anemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z713-F1 | alphafold | PREDICTED | 72.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z713.
Amino-acid sequence (158 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD37?
The strongest Open Targets associations for ANKRD37 are systemic scleroderma, esophageal squamous cell carcinoma, preeclampsia, childhood trauma measurement and smoking behaviour measurement.
How long is the ANKRD37 protein?
The Homo sapiens ANKRD37 protein (UniProt Q7Z713) is 158 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z713 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z713 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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