Filamin-A-interacting protein 1 (FILIP1)
Homo sapiens — UniProt Q7Z7B0
Data last refreshed: (UniProt release unknown)
Key facts
Filamin-A-interacting protein 1 (FILIP1) is a protein from Homo sapiens identified by UniProt accession Q7Z7B0, 1213 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q7Z7B0; gene symbol FILIP1.
- Organism: Homo sapiens.
- Length: 1213 amino acids.
- Top disease associations (Open Targets): body height, osteoarthritis, hip and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Filamin-A-interacting protein 1 |
|---|---|
| UniProt accession | Q7Z7B0 |
| Gene | FILIP1 |
| Organism | Homo sapiens |
| Length | 1213 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- body height · score 0.52
- osteoarthritis, hip · score 0.46
- lean body mass · score 0.46
- BMI-adjusted waist circumference · score 0.44
- BMI-adjusted hip circumference · score 0.43
- osteoarthritis · score 0.41
- fat body mass · score 0.41
- arthrogryposis multiplex congenita · score 0.37
- Intellectual disability · score 0.37
- vital capacity · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7B0-F1 | alphafold | PREDICTED | 66.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7B0.
Amino-acid sequence (1213 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FILIP1?
The strongest Open Targets associations for FILIP1 are body height, osteoarthritis, hip, lean body mass, BMI-adjusted waist circumference and BMI-adjusted hip circumference.
How long is the FILIP1 protein?
The Homo sapiens FILIP1 protein (UniProt Q7Z7B0) is 1213 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7B0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7B0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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