Ubiquitin-conjugating enzyme E2 Q1 (UBE2Q1)
Homo sapiens — UniProt Q7Z7E8
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-conjugating enzyme E2 Q1 (UBE2Q1) is a protein from Homo sapiens identified by UniProt accession Q7Z7E8, 422 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q7Z7E8; gene symbol UBE2Q1.
- Organism: Homo sapiens.
- Length: 422 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, neutrophil count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 Q1 |
|---|---|
| UniProt accession | Q7Z7E8 |
| Gene | UBE2Q1 |
| Organism | Homo sapiens |
| Length | 422 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.29
- neutrophil count · score 0.22
- leukocyte count · score 0.19
- monocyte count · score 0.19
- clear cell renal carcinoma · score 0.18
- rhabdomyosarcoma · score 0.15
- body height · score 0.09
- interleukin 6 receptor subunit alpha measurement · score 0.08
- hemoglobin measurement · score 0.06
- primary ovarian insufficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7E8-F1 | alphafold | PREDICTED | 77.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7E8.
Amino-acid sequence (422 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBE2Q1?
The strongest Open Targets associations for UBE2Q1 are FEV/FVC ratio, neutrophil count, leukocyte count, monocyte count and clear cell renal carcinoma.
How long is the UBE2Q1 protein?
The Homo sapiens UBE2Q1 protein (UniProt Q7Z7E8) is 422 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7E8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7E8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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