KH homology domain-containing protein 4 (KHDC4)
Homo sapiens — UniProt Q7Z7F0
Data last refreshed: (UniProt release unknown)
Key facts
KH homology domain-containing protein 4 (KHDC4) is a protein from Homo sapiens identified by UniProt accession Q7Z7F0, 614 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q7Z7F0; gene symbol KHDC4.
- Organism: Homo sapiens.
- Length: 614 amino acids.
- Top disease associations (Open Targets): total blood protein measurement, sex hormone-binding globulin measurement and oral squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | KH homology domain-containing protein 4 |
|---|---|
| UniProt accession | Q7Z7F0 |
| Gene | KHDC4 |
| Organism | Homo sapiens |
| Length | 614 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.12
- sex hormone-binding globulin measurement · score 0.12
- oral squamous cell carcinoma · score 0.08
- body mass index · score 0.06
- inflammatory bowel disease · score 0.04
- Crohn's disease · score 0.03
- vitamin D measurement · score 0.03
- Parkinson disease · score 0.02
- reticulocyte measurement · score 0.02
- cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7F0-F1 | alphafold | PREDICTED | 62.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7F0.
Amino-acid sequence (614 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KHDC4?
The strongest Open Targets associations for KHDC4 are total blood protein measurement, sex hormone-binding globulin measurement, oral squamous cell carcinoma, body mass index and inflammatory bowel disease.
How long is the KHDC4 protein?
The Homo sapiens KHDC4 protein (UniProt Q7Z7F0) is 614 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7F0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7F0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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