Large ribosomal subunit protein mL55 (MRPL55)

About Large ribosomal subunit protein mL55

Large ribosomal subunit protein mL55 (MRPL55) is a protein from Homo sapiens identified by UniProt accession Q7Z7F7, 128 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL55
UniProt accession	Q7Z7F7
Gene	MRPL55
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
hepatocellular carcinoma · score 0.07
insulin like growth factor measurement · score 0.05
hypertension · score 0.04
Alzheimer disease · score 0.01
Other metabolic disease · score 0.00
neoplasm · score 0.00
Neurodevelopmental disorder · score 0.00
lung adenocarcinoma · score 0.00
Bloom syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7Z7F7-F1	alphafold	PREDICTED	79.34	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7F7.

Amino-acid sequence (128 residues)

MAAVGSLLGR LRQSTVKATG PALRRLHTSS WRADSSRASL TRVHRQAYAR LYPVLLVKQD GSTIHIRYRE PRRMLAMPID LDTLSPEERR ARLRKREAQL QSRKEYEQEL SDDLHVERYR QFWTRTKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards