Target of Nesh-SH3 (ABI3BP)
Homo sapiens — UniProt Q7Z7G0
Data last refreshed: (UniProt release unknown)
Key facts
Target of Nesh-SH3 (ABI3BP) is a protein from Homo sapiens identified by UniProt accession Q7Z7G0, 1068 residues long. MolForge cross-references it against 0 known binders and 123 disease associations.
- UniProt accession: Q7Z7G0; gene symbol ABI3BP.
- Organism: Homo sapiens.
- Length: 1068 amino acids.
- Top disease associations (Open Targets): cup-to-disc ratio measurement, optic disc area measurement and joint hypermobility measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Target of Nesh-SH3 |
|---|---|
| UniProt accession | Q7Z7G0 |
| Gene | ABI3BP |
| Organism | Homo sapiens |
| Length | 1068 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (123)
Diseases linked to this target (Open Targets).
- cup-to-disc ratio measurement · score 0.35
- optic disc area measurement · score 0.33
- joint hypermobility measurement · score 0.30
- optic disc size measurement · score 0.27
- neoplasm · score 0.09
- cancer · score 0.08
- blood protein measurement · score 0.08
- Neoplasm of the lung · score 0.07
- major depressive disorder · score 0.06
- amelogenesis imperfecta · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7G0-F1 | alphafold | PREDICTED | 53.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7G0.
Amino-acid sequence (1068 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABI3BP?
The strongest Open Targets associations for ABI3BP are cup-to-disc ratio measurement, optic disc area measurement, joint hypermobility measurement, optic disc size measurement and neoplasm.
How long is the ABI3BP protein?
The Homo sapiens ABI3BP protein (UniProt Q7Z7G0) is 1068 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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