Ciliogenesis-associated TTC17-interacting protein (CATIP)
Homo sapiens — UniProt Q7Z7H3
Data last refreshed: (UniProt release unknown)
Key facts
Ciliogenesis-associated TTC17-interacting protein (CATIP) is a protein from Homo sapiens identified by UniProt accession Q7Z7H3, 387 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q7Z7H3; gene symbol CATIP.
- Organism: Homo sapiens.
- Length: 387 amino acids.
- Top disease associations (Open Targets): male infertility with azoospermia or oligozoospermia due to single gene mutation, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ciliogenesis-associated TTC17-interacting protein |
|---|---|
| UniProt accession | Q7Z7H3 |
| Gene | CATIP |
| Organism | Homo sapiens |
| Length | 387 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.37
- mean platelet volume · score 0.27
- platelet count · score 0.24
- serum gamma-glutamyl transferase measurement · score 0.22
- fat body mass · score 0.08
- lean body mass · score 0.08
- azoospermia · score 0.07
- sex hormone-binding globulin measurement · score 0.06
- systolic blood pressure · score 0.05
- male infertility with teratozoospermia due to single gene mutation · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7H3-F1 | alphafold | PREDICTED | 85.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7H3.
Amino-acid sequence (387 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CATIP?
The strongest Open Targets associations for CATIP are male infertility with azoospermia or oligozoospermia due to single gene mutation, mean platelet volume, platelet count, serum gamma-glutamyl transferase measurement and fat body mass.
How long is the CATIP protein?
The Homo sapiens CATIP protein (UniProt Q7Z7H3) is 387 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7H3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7H3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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