Large ribosomal subunit protein uL10m (MRPL10)
Homo sapiens — UniProt Q7Z7H8
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein uL10m (MRPL10) is a protein from Homo sapiens identified by UniProt accession Q7Z7H8, 261 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q7Z7H8; gene symbol MRPL10.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein uL10m |
|---|---|
| UniProt accession | Q7Z7H8 |
| Gene | MRPL10 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- lysosomal storage disease · score 0.27
- multiple sclerosis · score 0.27
- Parkinson disease · score 0.27
- Alzheimer disease · score 0.27
- pulse pressure measurement · score 0.18
- hair color · score 0.17
- prostate carcinoma · score 0.14
- type 2 diabetes mellitus · score 0.13
- balding measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7H8-F1 | alphafold | PREDICTED | 82.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7H8.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL10?
The strongest Open Targets associations for MRPL10 are neurodegenerative disease, lysosomal storage disease, multiple sclerosis, Parkinson disease and Alzheimer disease.
How long is the MRPL10 protein?
The Homo sapiens MRPL10 protein (UniProt Q7Z7H8) is 261 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7H8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7H8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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