LHFPL tetraspan subfamily member 4 protein (LHFPL4)
Homo sapiens — UniProt Q7Z7J7
Data last refreshed: (UniProt release unknown)
Key facts
LHFPL tetraspan subfamily member 4 protein (LHFPL4) is a protein from Homo sapiens identified by UniProt accession Q7Z7J7, 247 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q7Z7J7; gene symbol LHFPL4.
- Organism: Homo sapiens.
- Length: 247 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, fibrinogen measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LHFPL tetraspan subfamily member 4 protein |
|---|---|
| UniProt accession | Q7Z7J7 |
| Gene | LHFPL4 |
| Organism | Homo sapiens |
| Length | 247 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- fibrinogen measurement · score 0.13
- body mass index · score 0.08
- mean platelet volume · score 0.07
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- type 2 diabetes mellitus · score 0.06
- fat body mass · score 0.05
- C-reactive protein measurement · score 0.05
- body weight · score 0.05
- pentosuria · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7J7-F1 | alphafold | PREDICTED | 82.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7J7.
Amino-acid sequence (247 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LHFPL4?
The strongest Open Targets associations for LHFPL4 are neurodegenerative disease, fibrinogen measurement, body mass index, mean platelet volume and isolated asymptomatic elevation of creatine phosphokinase.
How long is the LHFPL4 protein?
The Homo sapiens LHFPL4 protein (UniProt Q7Z7J7) is 247 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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