Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1)
Homo sapiens — UniProt Q7Z7J9
Data last refreshed: (UniProt release unknown)
Key facts
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1) is a protein from Homo sapiens identified by UniProt accession Q7Z7J9, 78 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q7Z7J9; gene symbol CAMK2N1.
- Organism: Homo sapiens.
- Length: 78 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, hematocrit and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium/calmodulin-dependent protein kinase II inhibitor 1 |
|---|---|
| UniProt accession | Q7Z7J9 |
| Gene | CAMK2N1 |
| Organism | Homo sapiens |
| Length | 78 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.31
- hematocrit · score 0.30
- multiple sclerosis · score 0.29
- Alzheimer disease · score 0.29
- lysosomal storage disease · score 0.29
- neurodegenerative disease · score 0.29
- Parkinson disease · score 0.29
- cognitive function measurement · score 0.23
- type 2 diabetes mellitus · score 0.23
- red blood cell density measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7J9-F1 | alphafold | PREDICTED | 69.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7J9.
Amino-acid sequence (78 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAMK2N1?
The strongest Open Targets associations for CAMK2N1 are hemoglobin measurement, hematocrit, multiple sclerosis, Alzheimer disease and lysosomal storage disease.
How long is the CAMK2N1 protein?
The Homo sapiens CAMK2N1 protein (UniProt Q7Z7J9) is 78 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7J9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7J9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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