COX assembly mitochondrial protein homolog (CMC1)
Homo sapiens — UniProt Q7Z7K0
Data last refreshed: (UniProt release unknown)
Key facts
COX assembly mitochondrial protein homolog (CMC1) is a protein from Homo sapiens identified by UniProt accession Q7Z7K0, 106 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q7Z7K0; gene symbol CMC1.
- Organism: Homo sapiens.
- Length: 106 amino acids.
- Top disease associations (Open Targets): lymphocyte count, lymphocyte percentage of leukocytes and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COX assembly mitochondrial protein homolog |
|---|---|
| UniProt accession | Q7Z7K0 |
| Gene | CMC1 |
| Organism | Homo sapiens |
| Length | 106 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.44
- lymphocyte percentage of leukocytes · score 0.39
- Red cell distribution width · score 0.32
- platelet-to-lymphocyte ratio · score 0.31
- neutrophil percentage of leukocytes · score 0.30
- multiple sclerosis · score 0.29
- neurodegenerative disease · score 0.28
- lymphocyte:monocyte ratio · score 0.28
- monocyte percentage of leukocytes · score 0.28
- neutrophil-to-lymphocyte ratio · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7K0-F1 | alphafold | PREDICTED | 86.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7K0.
Amino-acid sequence (106 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CMC1?
The strongest Open Targets associations for CMC1 are lymphocyte count, lymphocyte percentage of leukocytes, Red cell distribution width, platelet-to-lymphocyte ratio and neutrophil percentage of leukocytes.
How long is the CMC1 protein?
The Homo sapiens CMC1 protein (UniProt Q7Z7K0) is 106 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7K0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7K0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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