Centromere protein V (CENPV)
Homo sapiens — UniProt Q7Z7K6
Data last refreshed: (UniProt release unknown)
Key facts
Centromere protein V (CENPV) is a protein from Homo sapiens identified by UniProt accession Q7Z7K6, 275 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q7Z7K6; gene symbol CENPV.
- Organism: Homo sapiens.
- Length: 275 amino acids.
- Top disease associations (Open Targets): risk-taking behaviour, smoking status measurement and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centromere protein V |
|---|---|
| UniProt accession | Q7Z7K6 |
| Gene | CENPV |
| Organism | Homo sapiens |
| Length | 275 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- risk-taking behaviour · score 0.19
- smoking status measurement · score 0.19
- hypertension · score 0.17
- diastolic blood pressure · score 0.17
- monocyte percentage of leukocytes · score 0.16
- self reported educational attainment · score 0.16
- granulocyte percentage of myeloid white cells · score 0.11
- emotional symptom measurement · score 0.09
- neutrophil count · score 0.08
- vital capacity · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7K6-F1 | alphafold | PREDICTED | 78.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7K6.
Amino-acid sequence (275 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CENPV?
The strongest Open Targets associations for CENPV are risk-taking behaviour, smoking status measurement, hypertension, diastolic blood pressure and monocyte percentage of leukocytes.
How long is the CENPV protein?
The Homo sapiens CENPV protein (UniProt Q7Z7K6) is 275 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7K6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7K6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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