Protein zer-1 homolog (ZER1)
Homo sapiens — UniProt Q7Z7L7
Data last refreshed: (UniProt release unknown)
Key facts
Protein zer-1 homolog (ZER1) is a protein from Homo sapiens identified by UniProt accession Q7Z7L7, 766 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q7Z7L7; gene symbol ZER1.
- Organism: Homo sapiens.
- Length: 766 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, waist-hip ratio and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein zer-1 homolog |
|---|---|
| UniProt accession | Q7Z7L7 |
| Gene | ZER1 |
| Organism | Homo sapiens |
| Length | 766 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.15
- waist-hip ratio · score 0.10
- serum gamma-glutamyl transferase measurement · score 0.09
- low density lipoprotein cholesterol measurement · score 0.08
- alcohol drinking · score 0.07
- sex hormone-binding globulin measurement · score 0.07
- thyroid disease · score 0.07
- total cholesterol measurement · score 0.06
- alcohol consumption measurement · score 0.06
- cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7L7-F1 | alphafold | PREDICTED | 90.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7L7.
Amino-acid sequence (766 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZER1?
The strongest Open Targets associations for ZER1 are BMI-adjusted waist-hip ratio, waist-hip ratio, serum gamma-glutamyl transferase measurement, low density lipoprotein cholesterol measurement and alcohol drinking.
How long is the ZER1 protein?
The Homo sapiens ZER1 protein (UniProt Q7Z7L7) is 766 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7L7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7L7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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