Zinc finger and SCAN domain-containing protein 2 (ZSCAN2)
Homo sapiens — UniProt Q7Z7L9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and SCAN domain-containing protein 2 (ZSCAN2) is a protein from Homo sapiens identified by UniProt accession Q7Z7L9, 614 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q7Z7L9; gene symbol ZSCAN2.
- Organism: Homo sapiens.
- Length: 614 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, BMI-adjusted waist circumference and BMI-adjusted hip circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 2 |
|---|---|
| UniProt accession | Q7Z7L9 |
| Gene | ZSCAN2 |
| Organism | Homo sapiens |
| Length | 614 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- BMI-adjusted waist circumference · score 0.41
- BMI-adjusted hip circumference · score 0.35
- schizophrenia · score 0.28
- physical activity measurement · score 0.27
- bipolar disorder · score 0.20
- aspartate aminotransferase measurement · score 0.18
- anorexia nervosa · score 0.18
- autism spectrum disorder · score 0.17
- diastolic blood pressure · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7L9-F1 | alphafold | PREDICTED | 69.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7L9.
Amino-acid sequence (614 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZSCAN2?
The strongest Open Targets associations for ZSCAN2 are neurodegenerative disease, BMI-adjusted waist circumference, BMI-adjusted hip circumference, schizophrenia and physical activity measurement.
How long is the ZSCAN2 protein?
The Homo sapiens ZSCAN2 protein (UniProt Q7Z7L9) is 614 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7L9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7L9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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