N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 8 (B3GNT8)
Homo sapiens — UniProt Q7Z7M8
Data last refreshed: (UniProt release unknown)
Key facts
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 8 (B3GNT8) is a protein from Homo sapiens identified by UniProt accession Q7Z7M8, 397 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q7Z7M8; gene symbol B3GNT8.
- Organism: Homo sapiens.
- Length: 397 amino acids.
- Top disease associations (Open Targets): body height, blood protein measurement and hair shape measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 8 |
|---|---|
| UniProt accession | Q7Z7M8 |
| Gene | B3GNT8 |
| Organism | Homo sapiens |
| Length | 397 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- blood protein measurement · score 0.19
- hair shape measurement · score 0.14
- glioblastoma multiforme · score 0.13
- BMI-adjusted waist circumference · score 0.12
- lean body mass · score 0.12
- total blood protein measurement · score 0.12
- balding measurement · score 0.11
- BMI-adjusted hip circumference · score 0.11
- Red cell distribution width · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7M8-F1 | alphafold | PREDICTED | 87.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7M8.
Amino-acid sequence (397 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B3GNT8?
The strongest Open Targets associations for B3GNT8 are body height, blood protein measurement, hair shape measurement, glioblastoma multiforme and BMI-adjusted waist circumference.
How long is the B3GNT8 protein?
The Homo sapiens B3GNT8 protein (UniProt Q7Z7M8) is 397 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7M8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7M8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.