Polypeptide N-acetylgalactosaminyltransferase 5 (GALNT5)
Homo sapiens — UniProt Q7Z7M9
Data last refreshed: (UniProt release unknown)
Key facts
Polypeptide N-acetylgalactosaminyltransferase 5 (GALNT5) is a protein from Homo sapiens identified by UniProt accession Q7Z7M9, 940 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q7Z7M9; gene symbol GALNT5.
- Organism: Homo sapiens.
- Length: 940 amino acids.
- Top disease associations (Open Targets): body height, phosphate measurement and blood phosphate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 5 |
|---|---|
| UniProt accession | Q7Z7M9 |
| Gene | GALNT5 |
| Organism | Homo sapiens |
| Length | 940 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- body height · score 0.38
- phosphate measurement · score 0.34
- blood phosphate measurement · score 0.31
- neurodegenerative disease · score 0.23
- neurofibrillary tangles measurement · score 0.19
- glioblastoma multiforme · score 0.13
- metabolite measurement · score 0.05
- central nervous system cancer · score 0.05
- cholangiocarcinoma · score 0.04
- lung carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7M9-F1 | alphafold | PREDICTED | 67.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7M9.
Amino-acid sequence (940 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT5?
The strongest Open Targets associations for GALNT5 are body height, phosphate measurement, blood phosphate measurement, neurodegenerative disease and neurofibrillary tangles measurement.
How long is the GALNT5 protein?
The Homo sapiens GALNT5 protein (UniProt Q7Z7M9) is 940 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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