Transmembrane protein 179B (TMEM179B)
Homo sapiens — UniProt Q7Z7N9
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 179B (TMEM179B) is a protein from Homo sapiens identified by UniProt accession Q7Z7N9, 219 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q7Z7N9; gene symbol TMEM179B.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and ulcerative colitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 179B |
|---|---|
| UniProt accession | Q7Z7N9 |
| Gene | TMEM179B |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.14
- mean platelet volume · score 0.04
- ulcerative colitis · score 0.01
- squamous cell carcinoma · score 0.00
- pancreatic adenocarcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z7N9-F1 | alphafold | PREDICTED | 85.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z7N9.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM179B?
The strongest Open Targets associations for TMEM179B are neurodegenerative disease, mean platelet volume, ulcerative colitis, squamous cell carcinoma and pancreatic adenocarcinoma.
How long is the TMEM179B protein?
The Homo sapiens TMEM179B protein (UniProt Q7Z7N9) is 219 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z7N9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z7N9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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