Ankyrin repeat domain-containing protein 23 (ANKRD23)
Homo sapiens — UniProt Q86SG2
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 23 (ANKRD23) is a protein from Homo sapiens identified by UniProt accession Q86SG2, 305 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q86SG2; gene symbol ANKRD23.
- Organism: Homo sapiens.
- Length: 305 amino acids.
- Top disease associations (Open Targets): mathematical ability, calcium measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 23 |
|---|---|
| UniProt accession | Q86SG2 |
| Gene | ANKRD23 |
| Organism | Homo sapiens |
| Length | 305 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.35
- calcium measurement · score 0.23
- body height · score 0.09
- mean corpuscular volume · score 0.04
- vital capacity · score 0.04
- neoplasm · score 0.04
- blood phosphate measurement · score 0.04
- cortical thickness · score 0.04
- systolic blood pressure · score 0.03
- sitting height measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86SG2-F1 | alphafold | PREDICTED | 81.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SG2.
Amino-acid sequence (305 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD23?
The strongest Open Targets associations for ANKRD23 are mathematical ability, calcium measurement, body height, mean corpuscular volume and vital capacity.
How long is the ANKRD23 protein?
The Homo sapiens ANKRD23 protein (UniProt Q86SG2) is 305 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86SG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86SG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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