Protein S100-A7A (S100A7A)
Homo sapiens — UniProt Q86SG5
Data last refreshed: (UniProt release unknown)
Key facts
Protein S100-A7A (S100A7A) is a protein from Homo sapiens identified by UniProt accession Q86SG5, 101 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q86SG5; gene symbol S100A7A.
- Organism: Homo sapiens.
- Length: 101 amino acids.
- Top disease associations (Open Targets): ulcerative colitis, lung adenocarcinoma and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein S100-A7A |
|---|---|
| UniProt accession | Q86SG5 |
| Gene | S100A7A |
| Organism | Homo sapiens |
| Length | 101 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- ulcerative colitis · score 0.23
- lung adenocarcinoma · score 0.18
- glioblastoma multiforme · score 0.17
- monocyte count · score 0.15
- cutaneous melanoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- genetic disorder · score 0.12
- breast adenocarcinoma · score 0.10
- psoriasis · score 0.09
- rosacea · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86SG5-F1 | alphafold | PREDICTED | 94.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SG5.
Amino-acid sequence (101 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with S100A7A?
The strongest Open Targets associations for S100A7A are ulcerative colitis, lung adenocarcinoma, glioblastoma multiforme, monocyte count and cutaneous melanoma.
How long is the S100A7A protein?
The Homo sapiens S100A7A protein (UniProt Q86SG5) is 101 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86SG5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86SG5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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