Lysozyme g-like protein 2 (LYG2)
Homo sapiens — UniProt Q86SG7
Data last refreshed: (UniProt release unknown)
Key facts
Lysozyme g-like protein 2 (LYG2) is a protein from Homo sapiens identified by UniProt accession Q86SG7, 212 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q86SG7; gene symbol LYG2.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): reticulocyte count, reticulocyte measurement and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysozyme g-like protein 2 |
|---|---|
| UniProt accession | Q86SG7 |
| Gene | LYG2 |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.30
- reticulocyte measurement · score 0.30
- FEV/FVC ratio · score 0.13
- body mass index · score 0.07
- cognitive function measurement · score 0.05
- uterine fibroid · score 0.04
- mathematical ability · score 0.03
- heel bone mineral density · score 0.02
- lifestyle measurement · score 0.02
- self reported educational attainment · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86SG7-F1 | alphafold | PREDICTED | 88.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SG7.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LYG2?
The strongest Open Targets associations for LYG2 are reticulocyte count, reticulocyte measurement, FEV/FVC ratio, body mass index and cognitive function measurement.
How long is the LYG2 protein?
The Homo sapiens LYG2 protein (UniProt Q86SG7) is 212 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86SG7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86SG7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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