Stearoyl-CoA desaturase 5 (SCD5)

About Stearoyl-CoA desaturase 5

Stearoyl-CoA desaturase 5 (SCD5) is a protein from Homo sapiens identified by UniProt accession Q86SK9, 330 residues long. MolForge cross-references it against 0 known binders and 203 disease associations.

Target properties

Protein name	Stearoyl-CoA desaturase 5
UniProt accession	Q86SK9
Gene	SCD5
Organism	Homo sapiens
Length	330 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (203)

Diseases linked to this target (Open Targets).

hearing loss, autosomal dominant 79 · score 0.55
reticulocyte measurement · score 0.45
monocyte count · score 0.45
lymphocyte count · score 0.44
eosinophil count · score 0.44
leukocyte count · score 0.43
neutrophil count · score 0.42
mean corpuscular volume · score 0.42
reticulocyte count · score 0.42
Immature Reticulocyte Fraction Measurement · score 0.42

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86SK9-F1	alphafold	PREDICTED	88.84	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SK9.

Amino-acid sequence (330 residues)

MPGPATDAGK IPFCDAKEEI RAGLESSEGG GGPERPGARG QRQNIVWRNV VLMSLLHLGA VYSLVLIPKA KPLTLLWAYF CFLLAALGVT AGAHRLWSHR SYRAKLPLRI FLAVANSMAF QNDIFEWSRD HRAHHKYSET DADPHNARRG FFFSHIGWLF VRKHRDVIEK GRKLDVTDLL ADPVVRIQRK YYKISVVLMC FVVPTLVPWY IWGESLWNSY FLASILRYTI SLNISWLVNS AAHMYGNRPY DKHISPRQNP LVALGAIGEG FHNYHHTFPF DYSASEFGLN FNPTTWFIDF MCWLGLATDR KRATKPMIEA RKARTGDSSA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards