Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10)
Homo sapiens — UniProt Q86SR1
Data last refreshed: (UniProt release unknown)
Key facts
Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10) is a protein from Homo sapiens identified by UniProt accession Q86SR1, 603 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q86SR1; gene symbol GALNT10.
- Organism: Homo sapiens.
- Length: 603 amino acids.
- Top disease associations (Open Targets): schizophrenia, autism spectrum disorder and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 10 |
|---|---|
| UniProt accession | Q86SR1 |
| Gene | GALNT10 |
| Organism | Homo sapiens |
| Length | 603 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.50
- autism spectrum disorder · score 0.39
- self reported educational attainment · score 0.33
- intelligence · score 0.32
- apolipoprotein A 1 measurement · score 0.29
- triglyceride measurement · score 0.29
- feeling tense measurement · score 0.26
- high density lipoprotein cholesterol measurement · score 0.25
- neuroticism measurement · score 0.23
- body mass index · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86SR1-F1 | alphafold | PREDICTED | 90.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SR1.
Amino-acid sequence (603 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT10?
The strongest Open Targets associations for GALNT10 are schizophrenia, autism spectrum disorder, self reported educational attainment, intelligence and apolipoprotein A 1 measurement.
How long is the GALNT10 protein?
The Homo sapiens GALNT10 protein (UniProt Q86SR1) is 603 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86SR1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86SR1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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