Immunoglobulin-like domain-containing receptor 1 (ILDR1)
Homo sapiens — UniProt Q86SU0
Data last refreshed: (UniProt release unknown)
Key facts
Immunoglobulin-like domain-containing receptor 1 (ILDR1) is a protein from Homo sapiens identified by UniProt accession Q86SU0, 546 residues long. MolForge cross-references it against 0 known binders and 146 disease associations.
- UniProt accession: Q86SU0; gene symbol ILDR1.
- Organism: Homo sapiens.
- Length: 546 amino acids.
- Top disease associations (Open Targets): deafness, hearing loss, autosomal recessive and nonsyndromic genetic hearing loss.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Immunoglobulin-like domain-containing receptor 1 |
|---|---|
| UniProt accession | Q86SU0 |
| Gene | ILDR1 |
| Organism | Homo sapiens |
| Length | 546 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (146)
Diseases linked to this target (Open Targets).
- deafness · score 0.68
- hearing loss, autosomal recessive · score 0.65
- nonsyndromic genetic hearing loss · score 0.45
- hearing loss · score 0.39
- age-related hearing impairment · score 0.37
- Rare genetic deafness · score 0.35
- autosomal dominant nonsyndromic hearing loss · score 0.34
- Hearing impairment · score 0.32
- Thyroid preparation use measurement · score 0.31
- glomerular filtration rate · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86SU0-F1 | alphafold | PREDICTED | 58.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86SU0.
Amino-acid sequence (546 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ILDR1?
The strongest Open Targets associations for ILDR1 are deafness, hearing loss, autosomal recessive, nonsyndromic genetic hearing loss, hearing loss and age-related hearing impairment.
How long is the ILDR1 protein?
The Homo sapiens ILDR1 protein (UniProt Q86SU0) is 546 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86SU0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86SU0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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