Protein PAT1 homolog 1 (PATL1)
Homo sapiens — UniProt Q86TB9
Data last refreshed: (UniProt release unknown)
Key facts
Protein PAT1 homolog 1 (PATL1) is a protein from Homo sapiens identified by UniProt accession Q86TB9, 770 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q86TB9; gene symbol PATL1.
- Organism: Homo sapiens.
- Length: 770 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, extranodal nasal NK/T cell lymphoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein PAT1 homolog 1 |
|---|---|
| UniProt accession | Q86TB9 |
| Gene | PATL1 |
| Organism | Homo sapiens |
| Length | 770 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- extranodal nasal NK/T cell lymphoma · score 0.07
- head and neck squamous cell carcinoma · score 0.07
- essential tremor · score 0.05
- body height · score 0.05
- Young adult-onset Parkinsonism · score 0.05
- Cranio-cervical dystonia with laryngeal and upper-limb involvement · score 0.05
- spinocerebellar ataxia type 20 · score 0.04
- Hereditary late-onset Parkinson disease · score 0.04
- isolated dystonia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86TB9-F1 | alphafold | PREDICTED | 61.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86TB9.
Amino-acid sequence (770 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PATL1?
The strongest Open Targets associations for PATL1 are neurodegenerative disease, extranodal nasal NK/T cell lymphoma, head and neck squamous cell carcinoma, essential tremor and body height.
How long is the PATL1 protein?
The Homo sapiens PATL1 protein (UniProt Q86TB9) is 770 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86TB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86TB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.