Tetraspanin-33 (TSPAN33)
Homo sapiens — UniProt Q86UF1
Data last refreshed: (UniProt release unknown)
Key facts
Tetraspanin-33 (TSPAN33) is a protein from Homo sapiens identified by UniProt accession Q86UF1, 283 residues long. MolForge cross-references it against 0 known binders and 340 disease associations.
- UniProt accession: Q86UF1; gene symbol TSPAN33.
- Organism: Homo sapiens.
- Length: 283 amino acids.
- Top disease associations (Open Targets): urate measurement, creatinine measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetraspanin-33 |
|---|---|
| UniProt accession | Q86UF1 |
| Gene | TSPAN33 |
| Organism | Homo sapiens |
| Length | 283 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (340)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.35
- creatinine measurement · score 0.31
- blood protein measurement · score 0.26
- uric acid measurement · score 0.25
- glomerular filtration rate · score 0.25
- hematocrit · score 0.22
- hemoglobin measurement · score 0.21
- cystatin C measurement · score 0.15
- alkaline phosphatase measurement · score 0.13
- systemic lupus erythematosus · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86UF1-F1 | alphafold | PREDICTED | 89.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86UF1.
Amino-acid sequence (283 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSPAN33?
The strongest Open Targets associations for TSPAN33 are urate measurement, creatinine measurement, blood protein measurement, uric acid measurement and glomerular filtration rate.
How long is the TSPAN33 protein?
The Homo sapiens TSPAN33 protein (UniProt Q86UF1) is 283 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86UF1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86UF1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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