Organic solute transporter subunit alpha (SLC51A)
Homo sapiens — UniProt Q86UW1
Data last refreshed: (UniProt release unknown)
Key facts
Organic solute transporter subunit alpha (SLC51A) is a protein from Homo sapiens identified by UniProt accession Q86UW1, 340 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q86UW1; gene symbol SLC51A.
- Organism: Homo sapiens.
- Length: 340 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): Spondylometaphyseal dysplasia - cone-rod dystrophy, spondylometaphyseal dysplasia-cone-rod dystrophy syndrome and cholestasis, progressive familial intrahepatic, 6.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Organic solute transporter subunit alpha |
|---|---|
| UniProt accession | Q86UW1 |
| Gene | SLC51A |
| Organism | Homo sapiens |
| Length | 340 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- Spondylometaphyseal dysplasia - cone-rod dystrophy · score 0.53
- spondylometaphyseal dysplasia-cone-rod dystrophy syndrome · score 0.53
- cholestasis, progressive familial intrahepatic, 6 · score 0.46
- serum metabolite measurement · score 0.42
- testosterone measurement · score 0.41
- mean corpuscular hemoglobin concentration · score 0.23
- blood metabolite measurement · score 0.22
- mean corpuscular hemoglobin · score 0.21
- mean corpuscular volume · score 0.20
- HbA1c measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86UW1-F1 | alphafold | PREDICTED | 82.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86UW1.
Amino-acid sequence (340 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC51A?
The strongest Open Targets associations for SLC51A are Spondylometaphyseal dysplasia - cone-rod dystrophy, spondylometaphyseal dysplasia-cone-rod dystrophy syndrome, cholestasis, progressive familial intrahepatic, 6, serum metabolite measurement and testosterone measurement.
How long is the SLC51A protein?
The Homo sapiens SLC51A protein (UniProt Q86UW1) is 340 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86UW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86UW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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