N-alpha-acetyltransferase 40 (NAA40)
Homo sapiens — UniProt Q86UY6
Data last refreshed: (UniProt release unknown)
Key facts
N-alpha-acetyltransferase 40 (NAA40) is a protein from Homo sapiens identified by UniProt accession Q86UY6, 237 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q86UY6; gene symbol NAA40.
- Organism: Homo sapiens.
- Length: 237 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, systolic blood pressure and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-alpha-acetyltransferase 40 |
|---|---|
| UniProt accession | Q86UY6 |
| Gene | NAA40 |
| Organism | Homo sapiens |
| Length | 237 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.21
- systolic blood pressure · score 0.09
- neoplasm · score 0.08
- schizophrenia · score 0.06
- bipolar disorder · score 0.05
- metabolite measurement · score 0.05
- unipolar depression · score 0.04
- autism spectrum disorder · score 0.04
- obsessive-compulsive disorder · score 0.04
- attention deficit hyperactivity disorder · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86UY6-F1 | alphafold | PREDICTED | 92.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86UY6.
Amino-acid sequence (237 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAA40?
The strongest Open Targets associations for NAA40 are low density lipoprotein cholesterol measurement, systolic blood pressure, neoplasm, schizophrenia and bipolar disorder.
How long is the NAA40 protein?
The Homo sapiens NAA40 protein (UniProt Q86UY6) is 237 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86UY6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86UY6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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