About Glucocorticoid-induced transcript 1 protein
Glucocorticoid-induced transcript 1 protein (GLCCI1) is a protein
from Homo sapiens identified by UniProt accession
Q86VQ1, 547 residues long.
MolForge cross-references it against 0 known binders and
77 disease associations.
Target properties
| Protein name | Glucocorticoid-induced transcript 1 protein |
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| UniProt accession | Q86VQ1 |
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| Gene | GLCCI1 |
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| Organism | Homo sapiens |
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| Length | 547 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (77)
Diseases linked to this target (Open Targets).
- basophil count · score 0.47
- neutrophil count · score 0.46
- eosinophil count · score 0.45
- self reported educational attainment · score 0.45
- leukocyte count · score 0.44
- body height · score 0.43
- myeloid white cell count · score 0.42
- intelligence · score 0.41
- BMI-adjusted hip circumference · score 0.39
- lymphocyte percentage of leukocytes · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VQ1-F1 | alphafold | PREDICTED | 53.17 | — |
Amino-acid sequence (547 residues)
MSTASSSSSS SSSQTPHPPS QRMRRSAAGS PPAVAAAGSG NGAGGGGGVG CAPAAGAGRL LQPIRATVPY QLLRGSQHSP TRPPVAAAAA SLGSLPGPGA ARGPSPSSPT PPAAAAPAEQ APRAKGRPRR SPESHRRSSS PERRSPGSPV CRADKAKSQQ VRTSSTIRRT SSLDTITGPY LTGQWPRDPH VHYPSCMKDK ATQTPSCWAE EGAEKRSHQR SASWGSADQL KEQIAKLRQQ LQRSKQSSRH SKEKDRQSPL HGNHITISHT QATGSRSVPM PLSNISVPKS SVSRVPCNVE GISPELEKVF IKENNGKEEV SKPLDIPDGR RAPLPAHYRS SSTRSIDTQT PSVQERSSSC SSHSPCVSPF CPPESQDGSP CSTEDLLYDR DKDSGSSSPL PKYASSPKPN NSYMFKREPP EGCERVKVFE EMASRQPISA PLFSCPDKNK VNFIPTGSAF CPVKLLGPLL PASDLMLKNS PNSGQSSALA TLTVEQLSSR VSFTSLSDDT STAGSMEASV QQPSQQQQLL QELQGEDHIS AQNYVII
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