Glucocorticoid-induced transcript 1 protein (GLCCI1)
Homo sapiens — UniProt Q86VQ1
Data last refreshed: (UniProt release unknown)
Key facts
Glucocorticoid-induced transcript 1 protein (GLCCI1) is a protein from Homo sapiens identified by UniProt accession Q86VQ1, 547 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q86VQ1; gene symbol GLCCI1.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): basophil count, neutrophil count and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glucocorticoid-induced transcript 1 protein |
|---|---|
| UniProt accession | Q86VQ1 |
| Gene | GLCCI1 |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- basophil count · score 0.47
- neutrophil count · score 0.46
- eosinophil count · score 0.45
- self reported educational attainment · score 0.45
- leukocyte count · score 0.44
- body height · score 0.43
- myeloid white cell count · score 0.42
- intelligence · score 0.41
- BMI-adjusted hip circumference · score 0.39
- lymphocyte percentage of leukocytes · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q86VQ1-F1 | alphafold | PREDICTED | 53.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q86VQ1.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLCCI1?
The strongest Open Targets associations for GLCCI1 are basophil count, neutrophil count, eosinophil count, self reported educational attainment and leukocyte count.
How long is the GLCCI1 protein?
The Homo sapiens GLCCI1 protein (UniProt Q86VQ1) is 547 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q86VQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q86VQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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